Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHM1Pleckstrin homology and RUN domain containing M1. (973 aa)    
Predicted Functional Partners:
RAB7A
RAB7A, member RAS oncogene family.
    
 0.993
MAP1LC3C
Microtubule associated protein 1 light chain 3 gamma.
    
 0.987
GABARAPL1
GABA type A receptor associated protein like 1.
    
 0.959
GABARAP
GABA type A receptor-associated protein.
    
 0.959
VPS39
VPS39 subunit of HOPS complex.
    
 
 0.954
GABARAPL2
GABA type A receptor associated protein like 2.
    
 0.953
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.953
VPS41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
    
 
 0.937
RAB7B
RAB7B, member RAS oncogene family.
    
 0.930
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
   
 
 0.925
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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