close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHM1Pleckstrin homology and RUN domain containing M1. (973 aa)    
Predicted Functional Partners:
UVRAG
UV radiation resistance associated.
    
 0.910
MAP1LC3C
Microtubule associated protein 1 light chain 3 gamma.
    
 
 0.894
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.747
RAB7A
RAB7A, member RAS oncogene family.
    
 
 0.730
GABARAPL2
GABA type A receptor associated protein like 2.
    
 
 0.671
VPS39
VPS39 subunit of HOPS complex.
    
 
 0.663
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.631
MAP1LC3B
Uncharacterized protein.
    
 
 0.615
ARL8B
ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.602
ARL8A
ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.602
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.