Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SNX1Sorting nexin 1. (522 aa)    
Predicted Functional Partners:
SNX2
Sorting nexin 2.
  
0.999
VPS26A
VPS26, retromer complex component A.
   
 0.980
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.976
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
0.971
H0Y1U3_OTOGA
PX domain-containing protein.
   
 0.971
VPS26B
VPS26, retromer complex component B.
   
 0.966
SNX32
Sorting nexin; Involved in several stages of intracellular trafficking.
   
0.951
SNX6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
0.951
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.950
SDF2L1
Stromal cell derived factor 2 like 1.
    
 
 0.926
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.