CYP4V2 protein (Otolemur garnettii) - STRING interaction network

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Score

CYP4V2

Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (520 aa)

Predicted Functional Partners:

CYB5R4

0.854

DIP2C

0.829

EPHX2

0.760

CYB5R1

0.756

CYP11A1

0.746

SUOX

0.744

LSS

0.744

PLA2G4A

0.740

CYP26C1

0.723

HSD17B7

0.722

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYB5R1	CYB5R4	ENSOGAP00000009969	ENSOGAP00000016780	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.907
CYB5R1	CYP11A1	ENSOGAP00000009969	ENSOGAP00000002938	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.572
CYB5R1	CYP26C1	ENSOGAP00000009969	ENSOGAP00000020570	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family.	0.641
CYB5R1	CYP4V2	ENSOGAP00000009969	ENSOGAP00000001798	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family.	0.756
CYB5R1	SUOX	ENSOGAP00000009969	ENSOGAP00000006314	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Sulfite oxidase.	0.971
CYB5R4	CYB5R1	ENSOGAP00000016780	ENSOGAP00000009969	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.907
CYB5R4	CYP11A1	ENSOGAP00000016780	ENSOGAP00000002938	Cytochrome b5 reductase 4.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.742
CYB5R4	CYP26C1	ENSOGAP00000016780	ENSOGAP00000020570	Cytochrome b5 reductase 4.	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family.	0.798
CYB5R4	CYP4V2	ENSOGAP00000016780	ENSOGAP00000001798	Cytochrome b5 reductase 4.	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family.	0.854
CYB5R4	EPHX2	ENSOGAP00000016780	ENSOGAP00000002855	Cytochrome b5 reductase 4.	Epoxide hydrolase 2.	0.587
CYB5R4	SUOX	ENSOGAP00000016780	ENSOGAP00000006314	Cytochrome b5 reductase 4.	Sulfite oxidase.	0.933
CYP11A1	CYB5R1	ENSOGAP00000002938	ENSOGAP00000009969	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.572
CYP11A1	CYB5R4	ENSOGAP00000002938	ENSOGAP00000016780	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome b5 reductase 4.	0.742
CYP11A1	CYP26C1	ENSOGAP00000002938	ENSOGAP00000020570	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family.	0.528
CYP11A1	CYP4V2	ENSOGAP00000002938	ENSOGAP00000001798	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family.	0.746
CYP11A1	DIP2C	ENSOGAP00000002938	ENSOGAP00000012056	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Disco interacting protein 2 homolog C.	0.429
CYP11A1	EPHX2	ENSOGAP00000002938	ENSOGAP00000002855	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Epoxide hydrolase 2.	0.471
CYP11A1	HSD17B7	ENSOGAP00000002938	ENSOGAP00000009838	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxysteroid 17-beta dehydrogenase 7.	0.856
CYP11A1	LSS	ENSOGAP00000002938	ENSOGAP00000008236	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.541
CYP11A1	PLA2G4A	ENSOGAP00000002938	ENSOGAP00000022026	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Phospholipase A2.	0.469