Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1078 aa)    
Predicted Functional Partners:
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
   
   0.996
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
   
 
 0.951
AKAP10
A-kinase anchoring protein 10.
    
 
 0.890
H0XJ67_OTOGA
Uncharacterized protein.
    
 
 0.874
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.858
IQSEC1
IQ motif and Sec7 domain 1.
     
 0.820
CSE1L
Chromosome segregation 1 like.
   
 
 0.804
PI4KB
Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation (By similarity). Involved in Golgi-to-plasma membrane trafficking (By similarity).
    
 
 0.798
ABCF3
ATP binding cassette subfamily F member 3.
    
 
 0.796
IQSEC2
IQ motif and Sec7 domain 2.
     
 0.793
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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