Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SQSTM1Sequestosome 1. (446 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.998
MAP1LC3A
Microtubule associated protein 1 light chain 3 alpha.
   
 0.998
GABARAPL2
GABA type A receptor associated protein like 2.
   
 0.997
NBR1
NBR1 autophagy cargo receptor.
    
 0.997
TBK1
TANK binding kinase 1.
    
 0.997
MAP1LC3B
Uncharacterized protein.
   
 0.996
MAP1LC3C
Microtubule associated protein 1 light chain 3 gamma.
   
 0.996
H0XD69_OTOGA
Uncharacterized protein.
   
 0.993
IRAK1
Interleukin 1 receptor associated kinase 1.
    
  0.991
KEAP1
Kelch like ECH associated protein 1.
    
 0.990
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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