CHAF1A protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CHAF1A

Chromatin assembly factor 1 subunit A. (954 aa)

Predicted Functional Partners:

CHAF1B

0.996

ASF1B

0.981

PCNA

0.981

ASF1A

0.977

CBX5

0.964

RBBP4

0.947

CBX1

0.935

RBBP7

0.921

SETDB1

0.920

H0WHB3_OTOGA

0.915

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	ASF1B	ENSOGAP00000019630	ENSOGAP00000004499	Anti-silencing function 1A histone chaperone.	Anti-silencing function 1B histone chaperone.	0.966
ASF1A	CHAF1A	ENSOGAP00000019630	ENSOGAP00000001965	Anti-silencing function 1A histone chaperone.	Chromatin assembly factor 1 subunit A.	0.977
ASF1A	CHAF1B	ENSOGAP00000019630	ENSOGAP00000017513	Anti-silencing function 1A histone chaperone.	Chromatin assembly factor 1 subunit B.	0.961
ASF1A	PCNA	ENSOGAP00000019630	ENSOGAP00000017004	Anti-silencing function 1A histone chaperone.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.875
ASF1A	RBBP4	ENSOGAP00000019630	ENSOGAP00000010411	Anti-silencing function 1A histone chaperone.	RB binding protein 4, chromatin remodeling factor.	0.907
ASF1A	RBBP7	ENSOGAP00000019630	ENSOGAP00000013427	Anti-silencing function 1A histone chaperone.	RB binding protein 7, chromatin remodeling factor.	0.907
ASF1B	ASF1A	ENSOGAP00000004499	ENSOGAP00000019630	Anti-silencing function 1B histone chaperone.	Anti-silencing function 1A histone chaperone.	0.966
ASF1B	CHAF1A	ENSOGAP00000004499	ENSOGAP00000001965	Anti-silencing function 1B histone chaperone.	Chromatin assembly factor 1 subunit A.	0.981
ASF1B	CHAF1B	ENSOGAP00000004499	ENSOGAP00000017513	Anti-silencing function 1B histone chaperone.	Chromatin assembly factor 1 subunit B.	0.980
ASF1B	H0WHB3_OTOGA	ENSOGAP00000004499	ENSOGAP00000000748	Anti-silencing function 1B histone chaperone.	Uncharacterized protein.	0.450
ASF1B	PCNA	ENSOGAP00000004499	ENSOGAP00000017004	Anti-silencing function 1B histone chaperone.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.875
ASF1B	RBBP4	ENSOGAP00000004499	ENSOGAP00000010411	Anti-silencing function 1B histone chaperone.	RB binding protein 4, chromatin remodeling factor.	0.846
ASF1B	RBBP7	ENSOGAP00000004499	ENSOGAP00000013427	Anti-silencing function 1B histone chaperone.	RB binding protein 7, chromatin remodeling factor.	0.846
CBX1	CBX5	ENSOGAP00000005054	ENSOGAP00000012061	Chromobox 1.	Chromobox 5.	0.969
CBX1	CHAF1A	ENSOGAP00000005054	ENSOGAP00000001965	Chromobox 1.	Chromatin assembly factor 1 subunit A.	0.935
CBX1	CHAF1B	ENSOGAP00000005054	ENSOGAP00000017513	Chromobox 1.	Chromatin assembly factor 1 subunit B.	0.901
CBX1	H0WHB3_OTOGA	ENSOGAP00000005054	ENSOGAP00000000748	Chromobox 1.	Uncharacterized protein.	0.425
CBX1	RBBP4	ENSOGAP00000005054	ENSOGAP00000010411	Chromobox 1.	RB binding protein 4, chromatin remodeling factor.	0.834
CBX1	RBBP7	ENSOGAP00000005054	ENSOGAP00000013427	Chromobox 1.	RB binding protein 7, chromatin remodeling factor.	0.834
CBX1	SETDB1	ENSOGAP00000005054	ENSOGAP00000009233	Chromobox 1.	SET domain bifurcated histone lysine methyltransferase 1.	0.762