Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SGPP1Sphingosine-1-phosphate phosphatase 1. (441 aa)    
Predicted Functional Partners:
SGPL1
Sphingosine-1-phosphate lyase 1.
    
 0.983
SPHK2
Sphingosine kinase 2.
   
 0.955
CERS2
Ceramide synthase 2.
    
 0.940
CERS3
Ceramide synthase 3.
    
 0.934
SPHK1
Sphingosine kinase 1.
   
 0.934
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
    
 0.929
CERS4
Ceramide synthase 4.
    
 0.927
H0XYL4_OTOGA
TLC domain-containing protein.
    
 0.927
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.925
ACER3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.925
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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