TRIP12 protein (Otolemur garnettii) - STRING interaction network

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Score

TRIP12

Thyroid hormone receptor interactor 12. (2042 aa)

Predicted Functional Partners:

UBR1

0.993

UBR2

0.993

UBA3

0.991

UBA7

0.990

UBA6

0.990

UBA1

0.990

LTN1

0.988

UBA52

0.985

UBA5

0.983

ATG7

0.983

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	LTN1	ENSOGAP00000014486	ENSOGAP00000003105	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Listerin E3 ubiquitin protein ligase 1.	0.611
ATG7	TRIP12	ENSOGAP00000014486	ENSOGAP00000001982	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.983
ATG7	UBA1	ENSOGAP00000014486	ENSOGAP00000013912	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.762
ATG7	UBA3	ENSOGAP00000014486	ENSOGAP00000006957	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 3.	0.915
ATG7	UBA5	ENSOGAP00000014486	ENSOGAP00000004345	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 5.	0.864
ATG7	UBA52	ENSOGAP00000014486	ENSOGAP00000015909	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.941
ATG7	UBA6	ENSOGAP00000014486	ENSOGAP00000013020	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 6.	0.776
ATG7	UBA7	ENSOGAP00000014486	ENSOGAP00000009332	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.762
ATG7	UBR1	ENSOGAP00000014486	ENSOGAP00000004652	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.622
ATG7	UBR2	ENSOGAP00000014486	ENSOGAP00000011340	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.622
LTN1	ATG7	ENSOGAP00000003105	ENSOGAP00000014486	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.611
LTN1	TRIP12	ENSOGAP00000003105	ENSOGAP00000001982	Listerin E3 ubiquitin protein ligase 1.	Thyroid hormone receptor interactor 12.	0.988
LTN1	UBA1	ENSOGAP00000003105	ENSOGAP00000013912	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.532
LTN1	UBA3	ENSOGAP00000003105	ENSOGAP00000006957	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin like modifier activating enzyme 3.	0.611
LTN1	UBA5	ENSOGAP00000003105	ENSOGAP00000004345	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin like modifier activating enzyme 5.	0.611
LTN1	UBA52	ENSOGAP00000003105	ENSOGAP00000015909	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.849
LTN1	UBA6	ENSOGAP00000003105	ENSOGAP00000013020	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin like modifier activating enzyme 6.	0.481
LTN1	UBA7	ENSOGAP00000003105	ENSOGAP00000009332	Listerin E3 ubiquitin protein ligase 1.	Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.	0.469
LTN1	UBR1	ENSOGAP00000003105	ENSOGAP00000004652	Listerin E3 ubiquitin protein ligase 1.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.800
LTN1	UBR2	ENSOGAP00000003105	ENSOGAP00000011340	Listerin E3 ubiquitin protein ligase 1.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.686