Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C6orf58Chromosome 6 open reading frame 58. (305 aa)    
Predicted Functional Partners:
ATAT1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
      
 0.645
SOGA3
Uncharacterized protein.
      
 0.624
CA6
Carbonic anhydrase 6; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.607
CSTA
Cystatin A; Belongs to the cystatin family.
      
 0.606
BPIFB1
BPI fold containing family B member 1.
   
  
 0.595
BPIFA2
BPI fold containing family A member 2.
   
  
 0.582
ATP6V1FNB
ATP6V1F neighbor.
      
 0.581
CCDC127
Coiled-coil domain containing 127.
      
 0.580
CFAP61
Cilia and flagella associated protein 61.
      
 0.564
KIAA0408
KIAA0408.
      
 0.563
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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