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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTTNCortactin. (550 aa)    
Predicted Functional Partners:
H0XXU4_OTOGA
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.929
ACTR3B
Uncharacterized protein; Belongs to the actin family.
   
 0.917
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
 0.909
STX5
Syntaxin 5; Belongs to the syntaxin family.
    
 0.905
USO1
USO1 vesicle transport factor.
   
 0.885
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
    
 0.878
H0WMW7_OTOGA
Uncharacterized protein.
   
 
 0.870
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules.
   
 0.814
WAS
WASP actin nucleation promoting factor.
   
 0.810
WASL
WASP like actin nucleation promoting factor.
   
 0.810
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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