Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H0WKS5_OTOGAUncharacterized protein. (460 aa)    
Predicted Functional Partners:
ATRN
Attractin.
    
   0.751
TMEM231
Uncharacterized protein.
    
   0.628
SPSB3
SplA/ryanodine receptor domain and SOCS box containing 3.
      
 0.628
OSBP2
Oxysterol-binding protein; Belongs to the OSBP family.
    
   0.613
TMEM106B
Transmembrane protein 106B.
    
   0.606
DDX41
Uncharacterized protein.
    
 0.597
ATRNL1
Attractin like 1.
    
   0.585
H0XZ99_OTOGA
Uncharacterized protein.
    
 0.492
IL4
Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.
    
 0.477
ICAM2
Intercellular adhesion molecule 2.
      
 0.467
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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