Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RAP2CRAP2C, member of RAS oncogene family. (183 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.972
RAP2B
RAP2B, member of RAS oncogene family.
   
   0.955
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.905
RHOC
Ras homolog family member C.
   
 0.890
MAP4K4
Mitogen-activated protein kinase kinase kinase kinase 4.
    
 
 0.884
RABGGTB
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
  0.858
AFDN
Afadin, adherens junction formation factor.
    
 0.848
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1.
    
 0.845
DUSP22
Dual specificity phosphatase 22.
   
   0.839
FUNDC2
FUN14 domain containing 2 (Predicted).
    
   0.837
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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