Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
IGFBP2Insulin like growth factor binding protein 2. (322 aa)    
Predicted Functional Partners:
IGF1
Insulin like growth factor 1.
    
 0.941
IGF2
Insulin-like growth factor II (Predicted).
   
 0.932
GHSR
Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.887
CDX1
Caudal type homeobox 1.
      
 0.886
ZFAT
Zinc finger and AT-hook domain containing.
      
 0.812
PLAG1
PLAG1 zinc finger.
      
 0.757
TCF7
Transcription factor 7.
      
 0.731
IGFBP7
Insulin like growth factor binding protein 7.
     
 0.719
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
      
 0.710
LCORL
Ligand dependent nuclear receptor corepressor like.
      
 0.710
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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