Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2754 aa)    
Predicted Functional Partners:
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
   
 0.995
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
   
 0.993
HTT
Huntingtin.
    
 0.991
MRVI1
Murine retrovirus integration site 1 homolog.
    
 0.981
ERLIN2
ER lipid raft associated 2.
    
 
 0.967
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
    
 0.954
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.948
CALML4
Calmodulin like 4.
    
 0.939
CA8
Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family.
    
 
 0.935
CALML6
Calmodulin like 6.
    
 0.932
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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