STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TINAGL1Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family. (467 aa)    
Predicted Functional Partners:
HSPG2
Heparan sulfate proteoglycan 2.
   
 
 0.711
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
      
 0.583
H0XAD5_OTOGA
Uncharacterized protein.
   
 
 0.519
GFRAL
GDNF family receptor alpha like.
      
 0.463
TMEM184A
Transmembrane protein 184A.
      
 0.456
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
      
 0.454
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
      
 0.451
FAM83B
Family with sequence similarity 83 member B.
      
 0.443
CNIH1
Cornichon family AMPA receptor auxiliary protein 1.
      
 0.416
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.