Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SNX27Sorting nexin family member 27 (Predicted). (913 aa)    
Predicted Functional Partners:
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.944
OTULIN
OTU deubiquitinase with linear linkage specificity.
    
 
 0.901
H0WYF7_OTOGA
CAP-ZIP_m domain-containing protein.
    
 
 0.880
TBC1D5
TBC1 domain family member 5.
    
 
 0.872
VPS26A
VPS26, retromer complex component A.
   
 
 0.853
VPS26B
VPS26, retromer complex component B.
   
 
 0.853
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.834
H0Y1J2_OTOGA
Metallophos_2 domain-containing protein.
    
 
 0.834
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
    
 
 0.787
VPS26C
VPS26 endosomal protein sorting factor C.
   
 
 0.765
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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