| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATIC | GART | ENSOGAP00000004505 | ENSOGAP00000014169 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ATIC | GLDC | ENSOGAP00000004505 | ENSOGAP00000015948 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.805 |
| ATIC | MTHFD1 | ENSOGAP00000004505 | ENSOGAP00000004699 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. | 0.987 |
| ATIC | MTHFD2 | ENSOGAP00000004505 | ENSOGAP00000008151 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Uncharacterized protein. | 0.969 |
| ATIC | MTHFD2L | ENSOGAP00000004505 | ENSOGAP00000002452 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.969 |
| ATIC | MTHFR | ENSOGAP00000004505 | ENSOGAP00000008700 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.868 |
| ATIC | MTR | ENSOGAP00000004505 | ENSOGAP00000013808 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.901 |
| ATIC | SHMT1 | ENSOGAP00000004505 | ENSOGAP00000011546 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.987 |
| ATIC | SHMT2 | ENSOGAP00000004505 | ENSOGAP00000001653 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.986 |
| ATIC | TYMS | ENSOGAP00000004505 | ENSOGAP00000021313 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Thymidylate synthetase. | 0.925 |
| GART | ATIC | ENSOGAP00000014169 | ENSOGAP00000004505 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.999 |
| GART | GLDC | ENSOGAP00000014169 | ENSOGAP00000015948 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.953 |
| GART | MTHFD1 | ENSOGAP00000014169 | ENSOGAP00000004699 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. | 0.998 |
| GART | MTHFD2 | ENSOGAP00000014169 | ENSOGAP00000008151 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Uncharacterized protein. | 0.995 |
| GART | MTHFD2L | ENSOGAP00000014169 | ENSOGAP00000002452 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.994 |
| GART | MTHFR | ENSOGAP00000014169 | ENSOGAP00000008700 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.929 |
| GART | MTR | ENSOGAP00000014169 | ENSOGAP00000013808 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.918 |
| GART | SHMT1 | ENSOGAP00000014169 | ENSOGAP00000011546 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.996 |
| GART | SHMT2 | ENSOGAP00000014169 | ENSOGAP00000001653 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.996 |
| GART | TYMS | ENSOGAP00000014169 | ENSOGAP00000021313 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Thymidylate synthetase. | 0.963 |