Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (579 aa)    
Predicted Functional Partners:
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
  
 0.999
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.999
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
   
 0.999
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
   
 0.998
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.996
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.996
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.996
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
    
 0.995
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.995
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.995
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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