CDK8 protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNC	CDK19	ENSOGAP00000000993	ENSOGAP00000021664	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 19.	0.995
CCNC	CDK8	ENSOGAP00000000993	ENSOGAP00000005874	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 8.	0.999
CCNC	MED1	ENSOGAP00000000993	ENSOGAP00000009434	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.998
CCNC	MED10	ENSOGAP00000000993	ENSOGAP00000005354	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.996
CCNC	MED12	ENSOGAP00000000993	ENSOGAP00000008051	Cyclin C; Belongs to the cyclin family.	Mediator complex subunit 12.	0.997
CCNC	MED13	ENSOGAP00000000993	ENSOGAP00000006696	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.998
CCNC	MED13L	ENSOGAP00000000993	ENSOGAP00000012864	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.992
CCNC	MED30	ENSOGAP00000000993	ENSOGAP00000017184	Cyclin C; Belongs to the cyclin family.	Mediator complex subunit 30.	0.992
CCNC	MED6	ENSOGAP00000000993	ENSOGAP00000001168	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.998
CCNC	MED7	ENSOGAP00000000993	ENSOGAP00000004895	Cyclin C; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.	0.994
CDK19	CCNC	ENSOGAP00000021664	ENSOGAP00000000993	Cyclin dependent kinase 19.	Cyclin C; Belongs to the cyclin family.	0.995
CDK19	CDK8	ENSOGAP00000021664	ENSOGAP00000005874	Cyclin dependent kinase 19.	Cyclin dependent kinase 8.	0.998
CDK19	MED1	ENSOGAP00000021664	ENSOGAP00000009434	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.991
CDK19	MED10	ENSOGAP00000021664	ENSOGAP00000005354	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.990
CDK19	MED12	ENSOGAP00000021664	ENSOGAP00000008051	Cyclin dependent kinase 19.	Mediator complex subunit 12.	0.991
CDK19	MED13	ENSOGAP00000021664	ENSOGAP00000006696	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.993
CDK19	MED13L	ENSOGAP00000021664	ENSOGAP00000012864	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.991
CDK19	MED30	ENSOGAP00000021664	ENSOGAP00000017184	Cyclin dependent kinase 19.	Mediator complex subunit 30.	0.991
CDK19	MED6	ENSOGAP00000021664	ENSOGAP00000001168	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.992
CDK19	MED7	ENSOGAP00000021664	ENSOGAP00000004895	Cyclin dependent kinase 19.	Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.	0.992