STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)    
Predicted Functional Partners:
CCNA2
Cyclin A2; Belongs to the cyclin family.
 
 
 0.997
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.985
CKS2
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.981
CDC20
Cell division cycle 20.
   
 0.979
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.975
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.972
CDC20B
Cell division cycle 20B.
   
 0.972
PLK1
Serine/threonine-protein kinase PLK.
   
0.971
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.967
BUB1B
Uncharacterized protein.
   
 0.967
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.