STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FERMT2Fermitin family member 2. (680 aa)    
Predicted Functional Partners:
ILK
Integrin linked kinase.
   
 
 0.899
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.858
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.785
LPXN
Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN).
    
 
 0.781
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 
 0.781
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.778
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
    
 0.775
H0XE40_OTOGA
Integrin beta; Belongs to the integrin beta chain family.
    
 0.767
ITGB4
Integrin beta.
   
 0.764
ITGB2
Integrin beta.
    
 0.759
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.