EMSY protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBX1	CBX5	ENSOGAP00000005054	ENSOGAP00000012061	Chromobox 1.	Chromobox 5.	0.969
CBX1	EMSY	ENSOGAP00000005054	ENSOGAP00000010239	Chromobox 1.	EMSY transcriptional repressor, BRCA2 interacting.	0.963
CBX1	HDAC1	ENSOGAP00000005054	ENSOGAP00000005101	Chromobox 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.461
CBX1	RBBP4	ENSOGAP00000005054	ENSOGAP00000010411	Chromobox 1.	RB binding protein 4, chromatin remodeling factor.	0.834
CBX5	CBX1	ENSOGAP00000012061	ENSOGAP00000005054	Chromobox 5.	Chromobox 1.	0.969
CBX5	EMSY	ENSOGAP00000012061	ENSOGAP00000010239	Chromobox 5.	EMSY transcriptional repressor, BRCA2 interacting.	0.908
CBX5	HDAC1	ENSOGAP00000012061	ENSOGAP00000005101	Chromobox 5.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.458
CBX5	RBBP4	ENSOGAP00000012061	ENSOGAP00000010411	Chromobox 5.	RB binding protein 4, chromatin remodeling factor.	0.905
DDIT4L	EMSY	ENSOGAP00000003051	ENSOGAP00000010239	DNA damage inducible transcript 4 like.	EMSY transcriptional repressor, BRCA2 interacting.	0.800
EMSY	CBX1	ENSOGAP00000010239	ENSOGAP00000005054	EMSY transcriptional repressor, BRCA2 interacting.	Chromobox 1.	0.963
EMSY	CBX5	ENSOGAP00000010239	ENSOGAP00000012061	EMSY transcriptional repressor, BRCA2 interacting.	Chromobox 5.	0.908
EMSY	DDIT4L	ENSOGAP00000010239	ENSOGAP00000003051	EMSY transcriptional repressor, BRCA2 interacting.	DNA damage inducible transcript 4 like.	0.800
EMSY	GATAD1	ENSOGAP00000010239	ENSOGAP00000009696	EMSY transcriptional repressor, BRCA2 interacting.	GATA zinc finger domain containing 1.	0.963
EMSY	HDAC1	ENSOGAP00000010239	ENSOGAP00000005101	EMSY transcriptional repressor, BRCA2 interacting.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.937
EMSY	HDAC2	ENSOGAP00000010239	ENSOGAP00000009863	EMSY transcriptional repressor, BRCA2 interacting.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.801
EMSY	PHF12	ENSOGAP00000010239	ENSOGAP00000007119	EMSY transcriptional repressor, BRCA2 interacting.	PHD finger protein 12.	0.963
EMSY	RBBP4	ENSOGAP00000010239	ENSOGAP00000010411	EMSY transcriptional repressor, BRCA2 interacting.	RB binding protein 4, chromatin remodeling factor.	0.792
EMSY	SIN3A	ENSOGAP00000010239	ENSOGAP00000000137	EMSY transcriptional repressor, BRCA2 interacting.	SIN3 transcription regulator family member A.	0.899
EMSY	SIN3B	ENSOGAP00000010239	ENSOGAP00000005433	EMSY transcriptional repressor, BRCA2 interacting.	SIN3 transcription regulator family member B.	0.973
GATAD1	EMSY	ENSOGAP00000009696	ENSOGAP00000010239	GATA zinc finger domain containing 1.	EMSY transcriptional repressor, BRCA2 interacting.	0.963