STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALYREFAly/REF export factor. (233 aa)    
Predicted Functional Partners:
THOC2
THO complex 2.
   
 0.994
NCBP2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 0.990
UPF3A
UPF3A regulator of nonsense mediated mRNA decay.
    
 0.989
NCBP1
Nuclear cap binding protein subunit 1.
    
 0.989
SRRM1
Serine and arginine repetitive matrix 1.
    
 0.988
RANBP2
RAN binding protein 2.
   
 0.988
SARNP
SAP domain containing ribonucleoprotein.
   
 0.986
EIF4A3
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.985
SRRT
Serrate, RNA effector molecule.
   
 0.985
H0Y1C6_OTOGA
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.985
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.