node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETS1 | ETS2 | ENSOGAP00000013850 | ENSOGAP00000005884 | ETS proto-oncogene 1, transcription factor. | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | 0.876 |
ETS1 | PAX2 | ENSOGAP00000013850 | ENSOGAP00000013678 | ETS proto-oncogene 1, transcription factor. | Paired box 2. | 0.887 |
ETS1 | RUNX1 | ENSOGAP00000013850 | ENSOGAP00000020115 | ETS proto-oncogene 1, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.901 |
ETS1 | RUNX2 | ENSOGAP00000013850 | ENSOGAP00000003469 | ETS proto-oncogene 1, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.901 |
ETS1 | RUNX3 | ENSOGAP00000013850 | ENSOGAP00000020044 | ETS proto-oncogene 1, transcription factor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.886 |
ETS2 | ETS1 | ENSOGAP00000005884 | ENSOGAP00000013850 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | ETS proto-oncogene 1, transcription factor. | 0.876 |
ETS2 | PAX2 | ENSOGAP00000005884 | ENSOGAP00000013678 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | Paired box 2. | 0.778 |
ETS2 | RUNX1 | ENSOGAP00000005884 | ENSOGAP00000020115 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.821 |
ETS2 | RUNX2 | ENSOGAP00000005884 | ENSOGAP00000003469 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.821 |
ETS2 | RUNX3 | ENSOGAP00000005884 | ENSOGAP00000020044 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.821 |
ETV5 | PAX2 | ENSOGAP00000004823 | ENSOGAP00000013678 | ETS variant 5. | Paired box 2. | 0.625 |
ETV5 | RUNX1 | ENSOGAP00000004823 | ENSOGAP00000020115 | ETS variant 5. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.726 |
ETV5 | RUNX2 | ENSOGAP00000004823 | ENSOGAP00000003469 | ETS variant 5. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.726 |
ETV5 | RUNX3 | ENSOGAP00000004823 | ENSOGAP00000020044 | ETS variant 5. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.723 |
GSC | PAX2 | ENSOGAP00000018267 | ENSOGAP00000013678 | Goosecoid homeobox. | Paired box 2. | 0.779 |
PAX2 | ETS1 | ENSOGAP00000013678 | ENSOGAP00000013850 | Paired box 2. | ETS proto-oncogene 1, transcription factor. | 0.887 |
PAX2 | ETS2 | ENSOGAP00000013678 | ENSOGAP00000005884 | Paired box 2. | Protein C-ets-2; Transcription factor; Belongs to the ETS family. | 0.778 |
PAX2 | ETV5 | ENSOGAP00000013678 | ENSOGAP00000004823 | Paired box 2. | ETS variant 5. | 0.625 |
PAX2 | GSC | ENSOGAP00000013678 | ENSOGAP00000018267 | Paired box 2. | Goosecoid homeobox. | 0.779 |
PAX2 | PAXIP1 | ENSOGAP00000013678 | ENSOGAP00000000630 | Paired box 2. | PAX interacting protein 1. | 0.647 |