STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
   
 0.999
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.999
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
 
 
 0.999
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.998
CDK1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
 
 
 0.997
LOC100943441
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
 
 
 0.997
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
 
 
 0.995
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
 
 
 0.995
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.994
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.991
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.