TDG protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSOGAP00000002066	ENSOGAP00000000381	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	H0XPU8_OTOGA	ENSOGAP00000002066	ENSOGAP00000018139	CREB binding protein.	BTB_2 domain-containing protein.	0.683
CREBBP	H0XQT3_OTOGA	ENSOGAP00000002066	ENSOGAP00000018475	CREB binding protein.	Small ubiquitin-related modifier.	0.621
CREBBP	H0Y0J5_OTOGA	ENSOGAP00000002066	ENSOGAP00000021888	CREB binding protein.	Small ubiquitin-related modifier.	0.966
CREBBP	KCTD2	ENSOGAP00000002066	ENSOGAP00000022291	CREB binding protein.	BTB domain-containing protein.	0.683
CREBBP	SUMO1	ENSOGAP00000002066	ENSOGAP00000019503	CREB binding protein.	Ubiquitin-like domain-containing protein.	0.947
CREBBP	SUMO3	ENSOGAP00000002066	ENSOGAP00000004215	CREB binding protein.	Small ubiquitin-related modifier.	0.621
CREBBP	TDG	ENSOGAP00000002066	ENSOGAP00000015235	CREB binding protein.	Thymine DNA glycosylase.	0.964
CREBBP	TP53	ENSOGAP00000002066	ENSOGAP00000015106	CREB binding protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.997
CREBBP	UBE2I	ENSOGAP00000002066	ENSOGAP00000001269	CREB binding protein.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.963
EP300	CREBBP	ENSOGAP00000000381	ENSOGAP00000002066	E1A binding protein p300.	CREB binding protein.	0.999
EP300	H0XPU8_OTOGA	ENSOGAP00000000381	ENSOGAP00000018139	E1A binding protein p300.	BTB_2 domain-containing protein.	0.683
EP300	H0XQT3_OTOGA	ENSOGAP00000000381	ENSOGAP00000018475	E1A binding protein p300.	Small ubiquitin-related modifier.	0.639
EP300	H0Y0J5_OTOGA	ENSOGAP00000000381	ENSOGAP00000021888	E1A binding protein p300.	Small ubiquitin-related modifier.	0.869
EP300	KCTD2	ENSOGAP00000000381	ENSOGAP00000022291	E1A binding protein p300.	BTB domain-containing protein.	0.683
EP300	SUMO1	ENSOGAP00000000381	ENSOGAP00000019503	E1A binding protein p300.	Ubiquitin-like domain-containing protein.	0.866
EP300	SUMO3	ENSOGAP00000000381	ENSOGAP00000004215	E1A binding protein p300.	Small ubiquitin-related modifier.	0.639
EP300	TDG	ENSOGAP00000000381	ENSOGAP00000015235	E1A binding protein p300.	Thymine DNA glycosylase.	0.856
EP300	TP53	ENSOGAP00000000381	ENSOGAP00000015106	E1A binding protein p300.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.997
EP300	UBE2I	ENSOGAP00000000381	ENSOGAP00000001269	E1A binding protein p300.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.890