MEF2C protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HDAC4	MEF2A	ENSOGAP00000004404	ENSOGAP00000007826	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte enhancer factor 2A.	0.974
HDAC4	MEF2B	ENSOGAP00000004404	ENSOGAP00000001510	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte enhancer factor 2B.	0.695
HDAC4	MEF2C	ENSOGAP00000004404	ENSOGAP00000017187	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte enhancer factor 2C.	0.978
HDAC4	MEF2D	ENSOGAP00000004404	ENSOGAP00000010050	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte enhancer factor 2D.	0.787
HDAC4	MYOD1	ENSOGAP00000004404	ENSOGAP00000016451	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.535
MAPK11	MAPK12	ENSOGAP00000012698	ENSOGAP00000012693	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.990
MAPK11	MAPK13	ENSOGAP00000012698	ENSOGAP00000002523	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.966
MAPK11	MAPK14	ENSOGAP00000012698	ENSOGAP00000002521	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.989
MAPK11	MEF2A	ENSOGAP00000012698	ENSOGAP00000007826	Mitogen-activated protein kinase.	Myocyte enhancer factor 2A.	0.977
MAPK11	MEF2B	ENSOGAP00000012698	ENSOGAP00000001510	Mitogen-activated protein kinase.	Myocyte enhancer factor 2B.	0.924
MAPK11	MEF2C	ENSOGAP00000012698	ENSOGAP00000017187	Mitogen-activated protein kinase.	Myocyte enhancer factor 2C.	0.974
MAPK11	MEF2D	ENSOGAP00000012698	ENSOGAP00000010050	Mitogen-activated protein kinase.	Myocyte enhancer factor 2D.	0.799
MAPK11	MYOD1	ENSOGAP00000012698	ENSOGAP00000016451	Mitogen-activated protein kinase.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.658
MAPK12	MAPK11	ENSOGAP00000012693	ENSOGAP00000012698	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.990
MAPK12	MAPK13	ENSOGAP00000012693	ENSOGAP00000002523	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.990
MAPK12	MAPK14	ENSOGAP00000012693	ENSOGAP00000002521	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.969
MAPK12	MEF2A	ENSOGAP00000012693	ENSOGAP00000007826	Mitogen-activated protein kinase.	Myocyte enhancer factor 2A.	0.966
MAPK12	MEF2B	ENSOGAP00000012693	ENSOGAP00000001510	Mitogen-activated protein kinase.	Myocyte enhancer factor 2B.	0.938
MAPK12	MEF2C	ENSOGAP00000012693	ENSOGAP00000017187	Mitogen-activated protein kinase.	Myocyte enhancer factor 2C.	0.971
MAPK12	MEF2D	ENSOGAP00000012693	ENSOGAP00000010050	Mitogen-activated protein kinase.	Myocyte enhancer factor 2D.	0.827