Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HRASHRas proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.981
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.971
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.970
H0XWA1_OTOGA
Uncharacterized protein.
    
 0.967
RASA1
RAS p21 protein activator 1.
   
 0.966
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
 0.965
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.965
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
  
 0.964
SHOC2
SHOC2 leucine rich repeat scaffold protein.
   
 0.964
RGL1
Ral guanine nucleotide dissociation stimulator like 1.
    
 0.964
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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