MNX1 protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CX3CL1	EGFR	ENSOGAP00000015455	ENSOGAP00000008154	C-X3-C motif chemokine ligand 1.	Receptor protein-tyrosine kinase.	0.618
CX3CL1	GDF15	ENSOGAP00000015455	ENSOGAP00000018336	C-X3-C motif chemokine ligand 1.	Growth differentiation factor 15.	0.840
CX3CL1	GET3	ENSOGAP00000015455	ENSOGAP00000010918	C-X3-C motif chemokine ligand 1.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.818
CX3CL1	MNX1	ENSOGAP00000015455	ENSOGAP00000018416	C-X3-C motif chemokine ligand 1.	Motor neuron and pancreas homeobox 1.	0.634
CX3CL1	PTGS1	ENSOGAP00000015455	ENSOGAP00000002733	C-X3-C motif chemokine ligand 1.	Prostaglandin-endoperoxide synthase 1.	0.737
CX3CL1	TSPAN2	ENSOGAP00000015455	ENSOGAP00000010315	C-X3-C motif chemokine ligand 1.	Tetraspanin.	0.744
CX3CL1	VIPR1	ENSOGAP00000015455	ENSOGAP00000003401	C-X3-C motif chemokine ligand 1.	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.818
EGFR	CX3CL1	ENSOGAP00000008154	ENSOGAP00000015455	Receptor protein-tyrosine kinase.	C-X3-C motif chemokine ligand 1.	0.618
EGFR	GDF15	ENSOGAP00000008154	ENSOGAP00000018336	Receptor protein-tyrosine kinase.	Growth differentiation factor 15.	0.631
EGFR	GET3	ENSOGAP00000008154	ENSOGAP00000010918	Receptor protein-tyrosine kinase.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.618
EGFR	MNX1	ENSOGAP00000008154	ENSOGAP00000018416	Receptor protein-tyrosine kinase.	Motor neuron and pancreas homeobox 1.	0.638
EGFR	PTGS1	ENSOGAP00000008154	ENSOGAP00000002733	Receptor protein-tyrosine kinase.	Prostaglandin-endoperoxide synthase 1.	0.668
EGFR	TSPAN2	ENSOGAP00000008154	ENSOGAP00000010315	Receptor protein-tyrosine kinase.	Tetraspanin.	0.686
EGFR	VIPR1	ENSOGAP00000008154	ENSOGAP00000003401	Receptor protein-tyrosine kinase.	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.631
GDF15	CX3CL1	ENSOGAP00000018336	ENSOGAP00000015455	Growth differentiation factor 15.	C-X3-C motif chemokine ligand 1.	0.840
GDF15	EGFR	ENSOGAP00000018336	ENSOGAP00000008154	Growth differentiation factor 15.	Receptor protein-tyrosine kinase.	0.631
GDF15	GET3	ENSOGAP00000018336	ENSOGAP00000010918	Growth differentiation factor 15.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.788
GDF15	MNX1	ENSOGAP00000018336	ENSOGAP00000018416	Growth differentiation factor 15.	Motor neuron and pancreas homeobox 1.	0.686
GDF15	PTGS1	ENSOGAP00000018336	ENSOGAP00000002733	Growth differentiation factor 15.	Prostaglandin-endoperoxide synthase 1.	0.709
GDF15	TSPAN2	ENSOGAP00000018336	ENSOGAP00000010315	Growth differentiation factor 15.	Tetraspanin.	0.766