EIF2S1 protein (Otolemur garnettii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK2	EIF2AK4	ENSOGAP00000002290	ENSOGAP00000007957	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.916
EIF2AK2	EIF2S1	ENSOGAP00000002290	ENSOGAP00000018737	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 subunit alpha.	0.998
EIF2AK2	H0WIJ7_OTOGA	ENSOGAP00000002290	ENSOGAP00000001263	Eukaryotic translation initiation factor 2 alpha kinase 2.	eIF2B_5 domain-containing protein.	0.601
EIF2AK2	H0WWX1_OTOGA	ENSOGAP00000002290	ENSOGAP00000006911	Eukaryotic translation initiation factor 2 alpha kinase 2.	Tr-type G domain-containing protein.	0.606
EIF2AK2	H0XPA2_OTOGA	ENSOGAP00000002290	ENSOGAP00000017943	Eukaryotic translation initiation factor 2 alpha kinase 2.	eIF2B_5 domain-containing protein.	0.601
EIF2AK2	H0XQS1_OTOGA	ENSOGAP00000002290	ENSOGAP00000018463	Eukaryotic translation initiation factor 2 alpha kinase 2.	Tr-type G domain-containing protein.	0.606
EIF2AK2	PPP1R15A	ENSOGAP00000002290	ENSOGAP00000006707	Eukaryotic translation initiation factor 2 alpha kinase 2.	Protein phosphatase 1 regulatory subunit 15A.	0.468
EIF2AK4	EIF2AK2	ENSOGAP00000007957	ENSOGAP00000002290	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.916
EIF2AK4	EIF2S1	ENSOGAP00000007957	ENSOGAP00000018737	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 subunit alpha.	0.997
EIF2AK4	EIF3B	ENSOGAP00000007957	ENSOGAP00000005647	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form [...]	0.511
EIF2AK4	H0WIJ7_OTOGA	ENSOGAP00000007957	ENSOGAP00000001263	Eukaryotic translation initiation factor 2 alpha kinase 4.	eIF2B_5 domain-containing protein.	0.771
EIF2AK4	H0WWX1_OTOGA	ENSOGAP00000007957	ENSOGAP00000006911	Eukaryotic translation initiation factor 2 alpha kinase 4.	Tr-type G domain-containing protein.	0.904
EIF2AK4	H0XPA2_OTOGA	ENSOGAP00000007957	ENSOGAP00000017943	Eukaryotic translation initiation factor 2 alpha kinase 4.	eIF2B_5 domain-containing protein.	0.771
EIF2AK4	H0XQS1_OTOGA	ENSOGAP00000007957	ENSOGAP00000018463	Eukaryotic translation initiation factor 2 alpha kinase 4.	Tr-type G domain-containing protein.	0.904
EIF2S1	EIF2AK2	ENSOGAP00000018737	ENSOGAP00000002290	Eukaryotic translation initiation factor 2 subunit alpha.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.998
EIF2S1	EIF2AK4	ENSOGAP00000018737	ENSOGAP00000007957	Eukaryotic translation initiation factor 2 subunit alpha.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.997
EIF2S1	EIF3A	ENSOGAP00000018737	ENSOGAP00000004087	Eukaryotic translation initiation factor 2 subunit alpha.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.996
EIF2S1	EIF3B	ENSOGAP00000018737	ENSOGAP00000005647	Eukaryotic translation initiation factor 2 subunit alpha.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form [...]	0.997
EIF2S1	EIF3I	ENSOGAP00000018737	ENSOGAP00000015507	Eukaryotic translation initiation factor 2 subunit alpha.	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.998
EIF2S1	H0WIJ7_OTOGA	ENSOGAP00000018737	ENSOGAP00000001263	Eukaryotic translation initiation factor 2 subunit alpha.	eIF2B_5 domain-containing protein.	0.999