Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHOAUncharacterized protein. (142 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.974
ARHGEF1
Rho guanine nucleotide exchange factor 1.
   
 0.969
SMURF1
E3 ubiquitin-protein ligase.
    
 0.968
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
 0.968
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
   
 0.968
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.967
ARHGAP35
Rho GTPase activating protein 35.
    
 0.967
PKN1
Protein kinase N1.
    
 0.964
ARHGDIG
Rho GDP dissociation inhibitor gamma (Predicted).
   
 0.962
DIAPH1
Diaphanous related formin 1.
   
 0.960
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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