mutY protein (Campylobacter lari) - STRING interaction network

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second shell of interactors

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Score

mutY

A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD. (342 aa)

Predicted Functional Partners:

xth

0.873

mug

0.863

Cla_0132

0.806

Cla_0130

0.621

ung

0.586

hemN1

0.514

dnaN

0.508

pabB

0.473

polA

0.468

ogt

0.452

Your Current Organism:

Campylobacter lari

NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cla_0130	Cla_0132	Cla_0130	Cla_0132	Conserved hypothetical protein.	Pfam match to PF04055.12 Radical_SAM.	0.609
Cla_0130	mutY	Cla_0130	Cla_0131	Conserved hypothetical protein.	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	0.621
Cla_0130	ung	Cla_0130	Cla_0126	Conserved hypothetical protein.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.614
Cla_0132	Cla_0130	Cla_0132	Cla_0130	Pfam match to PF04055.12 Radical_SAM.	Conserved hypothetical protein.	0.609
Cla_0132	mutY	Cla_0132	Cla_0131	Pfam match to PF04055.12 Radical_SAM.	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	0.806
Cla_0132	ung	Cla_0132	Cla_0126	Pfam match to PF04055.12 Radical_SAM.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.458
dnaN	mutY	Cla_0002	Cla_0131	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	0.508
dnaN	polA	Cla_0002	Cla_1341	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.996
dnaN	ung	Cla_0002	Cla_0126	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.653
dnaN	xth	Cla_0002	Cla_0045	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III; Pfam match to PF03372.14 Exo_endo_phos.	0.905
hemN1	mutY	Cla_0667	Cla_0131	Oxygen-independent coproporphyrinogen III oxidase HemN, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	0.514
mug	mutY	Cla_0082	Cla_0131	Conserved hypothetical protein.	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	0.863
mug	polA	Cla_0082	Cla_1341	Conserved hypothetical protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.411
mug	xth	Cla_0082	Cla_0045	Conserved hypothetical protein.	Exodeoxyribonuclease III; Pfam match to PF03372.14 Exo_endo_phos.	0.777
mutY	Cla_0130	Cla_0131	Cla_0130	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	Conserved hypothetical protein.	0.621
mutY	Cla_0132	Cla_0131	Cla_0132	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	Pfam match to PF04055.12 Radical_SAM.	0.806
mutY	dnaN	Cla_0131	Cla_0002	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.508
mutY	hemN1	Cla_0131	Cla_0667	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	Oxygen-independent coproporphyrinogen III oxidase HemN, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.514
mutY	mug	Cla_0131	Cla_0082	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	Conserved hypothetical protein.	0.863
mutY	ogt	Cla_0131	Cla_0973	A/G-specific adenine glycosylase; Pfam match to PF00730.16 HhH-GPD.	methylated-DNA--protein-cysteine methyltransferase; Pfam match to PF01035.11 DNA_binding_1.	0.452