STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cysQ3'(2'),5'-bisphosphate nucleotidase; Pfam match to PF00459.16 Inositol_P. (231 aa)    
Predicted Functional Partners:
sat
Sulfate adenylyltransferase, putative.
  
 
 0.917
Cla_0157
Hypothetical protein.
       0.825
cysC
Pfam match to PF01583.11 APS_kinase.
 
  
 0.683
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.670
bisC
Biotin sulfoxide reductase; Pfam matches to PF00384.13 Molybdopterin, and to PF01568.12 Molydop_binding; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
      
 0.658
mqo
Malate:quinone oxidoreductase; Pfam match to PF01266.15 DAO.
      
 0.658
hyaC
Ni/Fe hydrogenase, cytochrome b subunit; Pfam match to PF01292.11 Ni_hydr_CYTB.
      
 0.658
mutS
Mismatch repair ATPase MutS, MutS2 family; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
      
 0.658
Cla_0159
Na+/H+ antiporter; Pfam match to PF00999.12 Na_H_Exchanger.
     
 0.642
bioB
Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
       0.635
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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