STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folBDihydroneopterin aldolase. (105 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam match to PF01288.11 HPPK.
  
 
 0.991
folP
Dihydropteroate synthase; Pfam match to PF00809.13 Pterin_bind.
  
 
 0.991
folE
Pfam match to PF01227.13 GTP_cyclohydroI.
  
  
 0.917
cosR
Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C.
  
  
 0.881
plsY
Conserved hypothetical protein (DUF205 domain protein); Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
  
    0.806
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.624
pta
Phosphate acetyltransferase; Pfam match to PF01515.10 PTA_PTB.
      
 0.609
folC
Folylpolyglutamate synthase/dihydrofolate synthase; Pfam match to PF08245.3 Mur_ligase_M.
  
  
 0.608
Cla_1278
Putative purine NTP pyrophosphatase - RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.571
ribD
Riboflavin biosynthesis protein; Pfam match to PF00383.13 dCMP_cyt_deam_1.
  
  
 0.550
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.