| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA | cosR | Cla_0640 | Cla_0175 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | 0.670 |
| ackA | fdxB | Cla_0640 | Cla_0174 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Ferredoxin; Pfam match to PF00037.18 Fer4. | 0.680 |
| ackA | folB | Cla_0640 | Cla_0176 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Dihydroneopterin aldolase. | 0.661 |
| ackA | pyk | Cla_0640 | Cla_0479 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family. | 0.745 |
| cosR | ackA | Cla_0175 | Cla_0640 | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.670 |
| cosR | fdxB | Cla_0175 | Cla_0174 | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | Ferredoxin; Pfam match to PF00037.18 Fer4. | 0.889 |
| cosR | folB | Cla_0175 | Cla_0176 | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | Dihydroneopterin aldolase. | 0.921 |
| cosR | plsY | Cla_0175 | Cla_0177 | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | Conserved hypothetical protein (DUF205 domain protein); Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.663 |
| cosR | pyk | Cla_0175 | Cla_0479 | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family. | 0.658 |
| fdxB | ackA | Cla_0174 | Cla_0640 | Ferredoxin; Pfam match to PF00037.18 Fer4. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.680 |
| fdxB | cosR | Cla_0174 | Cla_0175 | Ferredoxin; Pfam match to PF00037.18 Fer4. | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | 0.889 |
| fdxB | folB | Cla_0174 | Cla_0176 | Ferredoxin; Pfam match to PF00037.18 Fer4. | Dihydroneopterin aldolase. | 0.849 |
| fdxB | plsY | Cla_0174 | Cla_0177 | Ferredoxin; Pfam match to PF00037.18 Fer4. | Conserved hypothetical protein (DUF205 domain protein); Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.524 |
| fdxB | pyk | Cla_0174 | Cla_0479 | Ferredoxin; Pfam match to PF00037.18 Fer4. | Pyruvate kinase; Pfam matches to PF00224.12 PK, and to PF02887.7 PK_C; Belongs to the pyruvate kinase family. | 0.665 |
| folB | ackA | Cla_0176 | Cla_0640 | Dihydroneopterin aldolase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.661 |
| folB | cosR | Cla_0176 | Cla_0175 | Dihydroneopterin aldolase. | Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C. | 0.921 |
| folB | fdxB | Cla_0176 | Cla_0174 | Dihydroneopterin aldolase. | Ferredoxin; Pfam match to PF00037.18 Fer4. | 0.849 |
| folB | folC | Cla_0176 | Cla_1042 | Dihydroneopterin aldolase. | Folylpolyglutamate synthase/dihydrofolate synthase; Pfam match to PF08245.3 Mur_ligase_M. | 0.581 |
| folB | folE | Cla_0176 | Cla_1481 | Dihydroneopterin aldolase. | Pfam match to PF01227.13 GTP_cyclohydroI. | 0.912 |
| folB | folK | Cla_0176 | Cla_0232 | Dihydroneopterin aldolase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam match to PF01288.11 HPPK. | 0.990 |