STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plsYConserved hypothetical protein (DUF205 domain protein); Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (203 aa)    
Predicted Functional Partners:
plsX
Fatty acidphospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.981
gpsA
Glycerol 3-phosphate dehydrogenase; Pfam matches to PF01210.14 NAD_Gly3P_dh_N, and to PF07479.5 NAD_Gly3P_dh_C; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 
 0.945
plsC
Pfam match to PF01553.12 Acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
  
 
 0.928
folB
Dihydroneopterin aldolase.
  
    0.806
cosR
Two-component response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00486.19 Trans_reg_C.
       0.632
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.496
ccpA
Cytochrome c551 peroxidase; Pfam match to PF03150.5 CCP_MauG.
       0.493
gppA
Phosphatase, Ppx/GppA family; Pfam match to PF02541.7 Ppx-GppA.
       0.485
fdxB
Ferredoxin; Pfam match to PF00037.18 Fer4.
       0.485
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
    0.453
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.