| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0217 | lpxC | Cla_0217 | Cla_0218 | Peptidase, M23/M37 family; Pfam match to PF01551.13 Peptidase_M23. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.804 |
| Cla_0217 | thrB | Cla_0217 | Cla_0220 | Peptidase, M23/M37 family; Pfam match to PF01551.13 Peptidase_M23. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.783 |
| Cla_0217 | tsaB | Cla_0217 | Cla_0219 | Peptidase, M23/M37 family; Pfam match to PF01551.13 Peptidase_M23. | Conserved hypothetical protein. | 0.824 |
| cysE | hom | Cla_0747 | Cla_1414 | Serine O-acetyltransferase. | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | 0.817 |
| cysE | metC | Cla_0747 | Cla_0279 | Serine O-acetyltransferase. | Cystathionase beta-lyase; Pfam match to PF01053.11 Cys_Met_Meta_PP. | 0.493 |
| cysE | sdaA | Cla_0747 | Cla_0085 | Serine O-acetyltransferase. | L-serine dehydratase; Pfam matches to PF03315.6 SDH_beta, and to PF03313.6 SDH_alpha; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.912 |
| cysE | thrB | Cla_0747 | Cla_0220 | Serine O-acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.830 |
| hom | cysE | Cla_1414 | Cla_0747 | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | Serine O-acetyltransferase. | 0.817 |
| hom | ilvE | Cla_1414 | Cla_1404 | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.857 |
| hom | metC | Cla_1414 | Cla_0279 | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | Cystathionase beta-lyase; Pfam match to PF01053.11 Cys_Met_Meta_PP. | 0.902 |
| hom | sdaA | Cla_1414 | Cla_0085 | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | L-serine dehydratase; Pfam matches to PF03315.6 SDH_beta, and to PF03313.6 SDH_alpha; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.813 |
| hom | thrB | Cla_1414 | Cla_0220 | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.993 |
| hom | thrC | Cla_1414 | Cla_0902 | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | Threonine synthase; Pfam match to PF00291.16 PALP. | 0.967 |
| ilvE | hom | Cla_1404 | Cla_1414 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | 0.857 |
| ilvE | thrB | Cla_1404 | Cla_0220 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.825 |
| lpxC | Cla_0217 | Cla_0218 | Cla_0217 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Peptidase, M23/M37 family; Pfam match to PF01551.13 Peptidase_M23. | 0.804 |
| lpxC | thrB | Cla_0218 | Cla_0220 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.783 |
| lpxC | tsaB | Cla_0218 | Cla_0219 | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Conserved hypothetical protein. | 0.787 |
| metC | cysE | Cla_0279 | Cla_0747 | Cystathionase beta-lyase; Pfam match to PF01053.11 Cys_Met_Meta_PP. | Serine O-acetyltransferase. | 0.493 |
| metC | hom | Cla_0279 | Cla_1414 | Cystathionase beta-lyase; Pfam match to PF01053.11 Cys_Met_Meta_PP. | Homoserine dehydrogenase; Pfam matches to PF03447.7 NAD_binding_3, and to PF00742.10 Homoserine_dh. | 0.902 |