| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0458 | nspC | Cla_0458 | Cla_0354 | Saccharopine dehydrogenase; Pfam match to PF03435.9 Saccharop_dh. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.846 |
| Cla_1077 | nspC | Cla_1077 | Cla_0354 | Conserved hypothetical protein. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.900 |
| cueO | moaD | Cla_0353 | Cla_0352 | Multicopper oxidase family protein; Pfam matches to PF07732.6 Cu-oxidase_3, and to PF07731.5 Cu-oxidase_2. | Molybdopterin converting factor, subunit 1; Pfam match to PF02597.11 ThiS. | 0.795 |
| cueO | moaE | Cla_0353 | Cla_0351 | Multicopper oxidase family protein; Pfam matches to PF07732.6 Cu-oxidase_3, and to PF07731.5 Cu-oxidase_2. | Molybdopterin converting factor, subunit 2; Pfam match to PF02391.8 MoaE. | 0.810 |
| cueO | moeA1 | Cla_0353 | Cla_0350 | Multicopper oxidase family protein; Pfam matches to PF07732.6 Cu-oxidase_3, and to PF07731.5 Cu-oxidase_2. | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.785 |
| cueO | nspC | Cla_0353 | Cla_0354 | Multicopper oxidase family protein; Pfam matches to PF07732.6 Cu-oxidase_3, and to PF07731.5 Cu-oxidase_2. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.534 |
| fdhC | nspC | Cla_0355 | Cla_0354 | Formate dehydrogenase, cytochrome b subunit. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.569 |
| guaA | guaB | Cla_0501 | Cla_1159 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | nspC | Cla_0501 | Cla_0354 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.520 |
| guaB | guaA | Cla_1159 | Cla_0501 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | hisIE | Cla_1159 | Cla_0104 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase; Pfam matches to PF01502.9 PRA-CH, and to PF01503.8 PRA-PH; In the N-terminal section; belongs to the PRA-CH family. | 0.505 |
| guaB | nspC | Cla_1159 | Cla_0354 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.549 |
| hisIE | guaB | Cla_0104 | Cla_1159 | phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase; Pfam matches to PF01502.9 PRA-CH, and to PF01503.8 PRA-PH; In the N-terminal section; belongs to the PRA-CH family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.505 |
| hisIE | nspC | Cla_0104 | Cla_0354 | phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase; Pfam matches to PF01502.9 PRA-CH, and to PF01503.8 PRA-PH; In the N-terminal section; belongs to the PRA-CH family. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.522 |
| moaD | cueO | Cla_0352 | Cla_0353 | Molybdopterin converting factor, subunit 1; Pfam match to PF02597.11 ThiS. | Multicopper oxidase family protein; Pfam matches to PF07732.6 Cu-oxidase_3, and to PF07731.5 Cu-oxidase_2. | 0.795 |
| moaD | moaE | Cla_0352 | Cla_0351 | Molybdopterin converting factor, subunit 1; Pfam match to PF02597.11 ThiS. | Molybdopterin converting factor, subunit 2; Pfam match to PF02391.8 MoaE. | 0.999 |
| moaD | moeA1 | Cla_0352 | Cla_0350 | Molybdopterin converting factor, subunit 1; Pfam match to PF02597.11 ThiS. | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.922 |
| moaD | nspC | Cla_0352 | Cla_0354 | Molybdopterin converting factor, subunit 1; Pfam match to PF02597.11 ThiS. | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. | 0.604 |
| moaE | cueO | Cla_0351 | Cla_0353 | Molybdopterin converting factor, subunit 2; Pfam match to PF02391.8 MoaE. | Multicopper oxidase family protein; Pfam matches to PF07732.6 Cu-oxidase_3, and to PF07731.5 Cu-oxidase_2. | 0.810 |
| moaE | moaD | Cla_0351 | Cla_0352 | Molybdopterin converting factor, subunit 2; Pfam match to PF02391.8 MoaE. | Molybdopterin converting factor, subunit 1; Pfam match to PF02597.11 ThiS. | 0.999 |