STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cla_0420TPR-domain containing protein; Pfam matches to PF00515.19 TPR_1, and to PF00515.19 TPR_1. (791 aa)    
Predicted Functional Partners:
htpG
Heat shock protein HtpG, chaperone Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.902
dnaK
Chaperone and heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.887
rpoB
DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.878
rpoC
DNA-directed RNA polymerase, beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.878
rsfS
Conserved hypothetical protein (DUF143 domain protein); Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
   0.864
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.848
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
   0.777
fliI
Flagellum-specific ATP synthase FliI; Pfam match to PF00006.16 ATP-synt_ab.
  
 
 0.748
Cla_0972
Conserved hypothetical protein, ankyrin repeat domain protein; Pfam match to PF00023.21 Ank.
 
 0.724
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Pfam matches to PF00044.15 Gp_dh_N, and to PF02800.11 Gp_dh_C; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
 
 0.706
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.