STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)    
Predicted Functional Partners:
frdA
Fumarate reductase, flavoprotein subunit; Pfam matches to PF00890.15 FAD_binding_2, and to PF02910.11 Succ_DH_flav_C.
 
 0.998
mdh
Malate dehydrogenase; Pfam matches to PF00056.14 Ldh_1_N, and to PF02866.9 Ldh_1_C; Belongs to the LDH/MDH superfamily.
  
 0.971
frdC
Fumarate reductase, cytochrome b subunit; Pfam match to PF02967.5 Fum_red_TM.
   
 
 0.963
frdB
Fumarate reductase, iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.954
mez
Malate oxidoreductase; Pfam matches to PF00390.10 malic, and to PF03949.6 Malic_M.
  
 
 0.953
mqo
Malate:quinone oxidoreductase; Pfam match to PF01266.15 DAO.
    
 0.944
Cla_0403
Conserved hypothetical protein.
    
  0.905
argH
Pfam match to PF00206.11 Lyase_1.
   
 
 0.817
aspB
Aspartate aminotransferase; Pfam match to PF00155.12 Aminotran_1_2.
    
 0.815
fdhC
Formate dehydrogenase, cytochrome b subunit.
     
  0.800
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.