| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaA | gmhA | Cla_0001 | Cla_0478 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.678 |
| gmhA | dnaA | Cla_0478 | Cla_0001 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.678 |
| gmhA | gmhB | Cla_0478 | Cla_0475 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | 0.999 |
| gmhA | hisB | Cla_0478 | Cla_0099 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase; Pfam matches to PF08645.2 PNK3P, and to PF00475.9 IGPD; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.826 |
| gmhA | kdtA | Cla_0478 | Cla_0999 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.861 |
| gmhA | kpsC | Cla_0478 | Cla_0318 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Capsular polysaccharide export protein KpsC; Pfam matches to PF05159.5 Capsule_synth, and to PF05159.5 Capsule_synth. | 0.810 |
| gmhA | kpsF | Cla_0478 | Cla_0294 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Arabinose-5-phosphate isomerase; Pfam matches to PF01380.13 SIS, and to PF00571.19 CBS; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.743 |
| gmhA | waaC | Cla_0478 | Cla_1247 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Lipopolysaccharide heptosyltransferase I; Pfam match to PF01075.8 Glyco_transf_9. | 0.849 |
| gmhA | waaD | Cla_0478 | Cla_0476 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | ADP-L-glycero-D-mannoheptose-6-epimerase; Pfam match to PF01370.12 Epimerase. | 0.976 |
| gmhA | waaE | Cla_0478 | Cla_0477 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | D,D-heptose 1-phosphate adenosyltransferase/7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.999 |
| gmhA | waaF | Cla_0478 | Cla_1226 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | Lipopolysaccharide heptosyltransferase II; Pfam match to PF01075.8 Glyco_transf_9. | 0.852 |
| gmhB | gmhA | Cla_0475 | Cla_0478 | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.999 |
| gmhB | kdtA | Cla_0475 | Cla_0999 | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.495 |
| gmhB | waaC | Cla_0475 | Cla_1247 | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | Lipopolysaccharide heptosyltransferase I; Pfam match to PF01075.8 Glyco_transf_9. | 0.901 |
| gmhB | waaD | Cla_0475 | Cla_0476 | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | ADP-L-glycero-D-mannoheptose-6-epimerase; Pfam match to PF01370.12 Epimerase. | 0.973 |
| gmhB | waaE | Cla_0475 | Cla_0477 | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | D,D-heptose 1-phosphate adenosyltransferase/7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.998 |
| gmhB | waaF | Cla_0475 | Cla_1226 | Conserved hypothetical protein, putative phosphatase; Possible pseudogene; Pfam match to PF08645.2 PNK3P. | Lipopolysaccharide heptosyltransferase II; Pfam match to PF01075.8 Glyco_transf_9. | 0.920 |
| hisB | gmhA | Cla_0099 | Cla_0478 | Imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase; Pfam matches to PF08645.2 PNK3P, and to PF00475.9 IGPD; In the N-terminal section; belongs to the histidinol- phosphatase family. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.826 |
| hisB | kpsF | Cla_0099 | Cla_0294 | Imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase; Pfam matches to PF08645.2 PNK3P, and to PF00475.9 IGPD; In the N-terminal section; belongs to the histidinol- phosphatase family. | Arabinose-5-phosphate isomerase; Pfam matches to PF01380.13 SIS, and to PF00571.19 CBS; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.484 |
| hisB | waaD | Cla_0099 | Cla_0476 | Imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase; Pfam matches to PF08645.2 PNK3P, and to PF00475.9 IGPD; In the N-terminal section; belongs to the histidinol- phosphatase family. | ADP-L-glycero-D-mannoheptose-6-epimerase; Pfam match to PF01370.12 Epimerase. | 0.442 |