STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cla_0491Conserved hypothetical protein; Pfam match to PF05036.4 SPOR. (268 aa)    
Predicted Functional Partners:
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.804
lysS
lysyl-tRNA synthetase; Pfam matches to PF01336.16 tRNA_anti, and to PF00152.11 tRNA-synt_2; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.764
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.764
Cla_0490
Conserved hypothetical protein (DUF1882 domain protein); Pfam match to PF08966.2 DUF1882.
       0.764
Cla_0486
Conserved hypothetical integral membrane protein, CvpA family; Pfam match to PF02674.7 Colicin_V.
       0.752
fur
Ferric uptake regulation protein; Pfam match to PF01475.10 FUR; Belongs to the Fur family.
       0.752
gatC
glu-tRNAGln amidotransferase, subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
       0.703
folC
Folylpolyglutamate synthase/dihydrofolate synthase; Pfam match to PF08245.3 Mur_ligase_M.
  
    0.613
fliA
Flagellar biosynthesis sigma factor, sigma-F; Pfam matches to PF04542.5 Sigma70_r2, and to PF04545.7 Sigma70_r4; Belongs to the sigma-70 factor family.
  
 
 0.549
coaX
Transcriptional activator, putative, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.536
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.