STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flgRSigma-54 dependent DNA-binding response regulator; Pfam matches to PF00072.15 Response_reg, and to PF00158.17 Sigma54_activat. (429 aa)    
Predicted Functional Partners:
flgE1
Flagellar hook protein FlgE; Pfam matches to PF00460.11 Flg_bb_rod, and to PF07559.5 FlaE.
 
  
 0.938
fliY
Flagellar motor switch protein FliY; Pfam match to PF01052.11 SpoA.
  
  
 0.925
flhG
Conserved hypothetical protein, ATPase, ParA family; Pfam match to PF01656.14 CbiA.
  
 
 0.910
flgS
Two-component sensor histidine kinase; Pfam matches to PF00512.16 HisKA, and to PF02518.17 HATPase_c.
 
 
 0.904
flhF
Flagellar biosynthesis (GTP-binding) protein FlhF; Pfam match to PF00448.13 SRP54.
  
  
 0.891
cheA
Chemotaxis protein CheA; Pfam matches to PF01627.14 Hpt, and to PF02895.5 H-kinase_dim.
  
 
 0.876
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.833
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.817
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
     
 0.809
flgD
Flagellar hook assembly protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.809
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.