STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derConserved hypothetical protein, predicted GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (461 aa)    
Predicted Functional Partners:
gpsA
Glycerol 3-phosphate dehydrogenase; Pfam matches to PF01210.14 NAD_Gly3P_dh_N, and to PF07479.5 NAD_Gly3P_dh_C; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.956
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
    0.887
rluB
Putative ribosomal pseudouridine synthase; Pfam matches to PF01479.16 S4, and to PF00849.13 PseudoU_synth_2; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.858
trpS
tryptophanyl-tRNA synthetase; Pfam match to PF00579.16 tRNA-synt_1b; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.804
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.804
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.777
pflB
Conserved hypothetical integral membrane protein (TPR domain protein); Pfam matches to PF00515.19 TPR_1, and to PF00515.19 TPR_1.
       0.773
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
 
  
 0.694
typA
GTP-binding protein TypA; Pfam matches to PF00009.18 GTP_EFTU, and to PF03144.16 GTP_EFTU_D2.
   
  
 0.687
Cla_0537
Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6.
       0.618
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.