| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0537 | Cla_0538 | Cla_0537 | Cla_0538 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 0.807 |
| Cla_0537 | aroK | Cla_0537 | Cla_0535 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.627 |
| Cla_0537 | der | Cla_0537 | Cla_0536 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Conserved hypothetical protein, predicted GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.618 |
| Cla_0537 | kdsA | Cla_0537 | Cla_0539 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.764 |
| Cla_0537 | nusB | Cla_0537 | Cla_0541 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.757 |
| Cla_0537 | pflB | Cla_0537 | Cla_0532 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Conserved hypothetical integral membrane protein (TPR domain protein); Pfam matches to PF00515.19 TPR_1, and to PF00515.19 TPR_1. | 0.679 |
| Cla_0537 | pyrF | Cla_0537 | Cla_0542 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.745 |
| Cla_0537 | ribH | Cla_0537 | Cla_0540 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.748 |
| Cla_0537 | serS | Cla_0537 | Cla_0533 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.612 |
| Cla_0537 | trpS | Cla_0537 | Cla_0534 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | tryptophanyl-tRNA synthetase; Pfam match to PF00579.16 tRNA-synt_1b; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.618 |
| Cla_0538 | Cla_0537 | Cla_0538 | Cla_0537 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 0.807 |
| Cla_0538 | aroK | Cla_0538 | Cla_0535 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.599 |
| Cla_0538 | der | Cla_0538 | Cla_0536 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Conserved hypothetical protein, predicted GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.570 |
| Cla_0538 | kdsA | Cla_0538 | Cla_0539 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.764 |
| Cla_0538 | nusB | Cla_0538 | Cla_0541 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.770 |
| Cla_0538 | pflB | Cla_0538 | Cla_0532 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Conserved hypothetical integral membrane protein (TPR domain protein); Pfam matches to PF00515.19 TPR_1, and to PF00515.19 TPR_1. | 0.563 |
| Cla_0538 | pyrF | Cla_0538 | Cla_0542 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.966 |
| Cla_0538 | ribH | Cla_0538 | Cla_0540 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.745 |
| Cla_0538 | serS | Cla_0538 | Cla_0533 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.565 |
| Cla_0538 | trpS | Cla_0538 | Cla_0534 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | tryptophanyl-tRNA synthetase; Pfam match to PF00579.16 tRNA-synt_1b; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.576 |