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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cla_0538Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. (453 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.966
pyrB
Aspartate carbamoyltransferase; Pfam matches to PF02729.12 OTCace_N, and to PF00185.15 OTCace; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.917
pyrC2
Dihydroorotase; Pfam match to PF01979.11 Amidohydro_1.
  
  
 0.905
pyrAa
Carbamoylphosphate synthase, small subunit; Pfam matches to PF00988.13 CPSase_sm_chain, and to PF00117.19 GATase; Belongs to the CarA family.
  
  
 0.882
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.875
carB
Carbamoylphosphate synthase, large subunit; Pfam matches to PF00289.13 CPSase_L_chain, and to PF02786.8 CPSase_L_D2; Belongs to the CarB family.
  
  
 0.873
Cla_0537
Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6.
     
 0.807
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.800
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.770
kdsA
3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family.
       0.764
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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