| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0537 | Cla_0538 | Cla_0537 | Cla_0538 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 0.807 |
| Cla_0537 | kdsA | Cla_0537 | Cla_0539 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.764 |
| Cla_0537 | nusB | Cla_0537 | Cla_0541 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.757 |
| Cla_0537 | pyrF | Cla_0537 | Cla_0542 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.745 |
| Cla_0537 | ribH | Cla_0537 | Cla_0540 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.748 |
| Cla_0538 | Cla_0537 | Cla_0538 | Cla_0537 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 0.807 |
| Cla_0538 | kdsA | Cla_0538 | Cla_0539 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.764 |
| Cla_0538 | nusB | Cla_0538 | Cla_0541 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.770 |
| Cla_0538 | pyrF | Cla_0538 | Cla_0542 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.966 |
| Cla_0538 | ribH | Cla_0538 | Cla_0540 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.745 |
| kdsA | Cla_0537 | Cla_0539 | Cla_0537 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 0.764 |
| kdsA | Cla_0538 | Cla_0539 | Cla_0538 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 0.764 |
| kdsA | kdsB | Cla_0539 | Cla_0903 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Pfam match to PF02348.10 CTP_transf_3; Belongs to the KdsB family. | 0.852 |
| kdsA | kdsC | Cla_0539 | Cla_0656 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Conserved hypothetical protein, putative YrbI family phosphatase. | 0.990 |
| kdsA | kdtA | Cla_0539 | Cla_0999 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.783 |
| kdsA | kpsF | Cla_0539 | Cla_0294 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Arabinose-5-phosphate isomerase; Pfam matches to PF01380.13 SIS, and to PF00571.19 CBS; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.987 |
| kdsA | lpxK | Cla_0539 | Cla_0901 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.746 |
| kdsA | nusB | Cla_0539 | Cla_0541 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.802 |
| kdsA | pyrF | Cla_0539 | Cla_0542 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.783 |
| kdsA | ribH | Cla_0539 | Cla_0540 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.801 |