| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cla_0537 | Cla_0538 | Cla_0537 | Cla_0538 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 0.825 |
| Cla_0537 | aroK | Cla_0537 | Cla_0535 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.651 |
| Cla_0537 | kdsA | Cla_0537 | Cla_0539 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.787 |
| Cla_0537 | nusB | Cla_0537 | Cla_0541 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.770 |
| Cla_0537 | pyrF | Cla_0537 | Cla_0542 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.767 |
| Cla_0537 | ribH | Cla_0537 | Cla_0540 | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.767 |
| Cla_0538 | Cla_0537 | Cla_0538 | Cla_0537 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 0.825 |
| Cla_0538 | aroK | Cla_0538 | Cla_0535 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.639 |
| Cla_0538 | kdsA | Cla_0538 | Cla_0539 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.787 |
| Cla_0538 | nusB | Cla_0538 | Cla_0541 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.767 |
| Cla_0538 | pyrF | Cla_0538 | Cla_0542 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.969 |
| Cla_0538 | ribH | Cla_0538 | Cla_0540 | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.767 |
| aroK | Cla_0537 | Cla_0535 | Cla_0537 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 0.651 |
| aroK | Cla_0538 | Cla_0535 | Cla_0538 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 0.639 |
| aroK | kdsA | Cla_0535 | Cla_0539 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | 0.734 |
| aroK | nusB | Cla_0535 | Cla_0541 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.694 |
| aroK | pyrF | Cla_0535 | Cla_0542 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.603 |
| aroK | ribH | Cla_0535 | Cla_0540 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.640 |
| kdsA | Cla_0537 | Cla_0539 | Cla_0537 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Conserved hypothetical integral membrane protein (DUF6 domain protein); Pfam match to PF00892.11 DUF6. | 0.787 |
| kdsA | Cla_0538 | Cla_0539 | Cla_0538 | 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase; Pfam match to PF00793.11 DAHP_synth_1; Belongs to the KdsA family. | Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease. | 0.787 |