STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (227 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.994
pyrB
Aspartate carbamoyltransferase; Pfam matches to PF02729.12 OTCace_N, and to PF00185.15 OTCace; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.974
Cla_0538
Purine/xanthine transport protein; Pfam match to PF00860.11 Xan_ur_permease.
  
  
 0.969
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.951
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.947
carB
Carbamoylphosphate synthase, large subunit; Pfam matches to PF00289.13 CPSase_L_chain, and to PF02786.8 CPSase_L_D2; Belongs to the CarB family.
  
  
 0.938
pyrC2
Dihydroorotase; Pfam match to PF01979.11 Amidohydro_1.
 
  
 0.925
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.916
pyrAa
Carbamoylphosphate synthase, small subunit; Pfam matches to PF00988.13 CPSase_sm_chain, and to PF00117.19 GATase; Belongs to the CarA family.
  
  
 0.902
maf
Septum formation protein Maf; Pfam match to PF02545.5 Maf; Belongs to the Maf family.
     
  0.900
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.