Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cla_0570Peptidase, M48 family; Pfam match to PF01435.9 Peptidase_M48. (395 aa)    
Predicted Functional Partners:
hemK
Modification methylase, HemK family; Pfam match to PF05175.5 MTS.
       0.825
Cla_0568
Probable integral membrane protein.
       0.752
Cla_1388
Conserved hypothetical protein, tetratricopeptide repeat domain protein family; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.
   
 
 0.744
flaC
Flagellin; Pfam match to PF00669.11 Flagellin_N.
       0.716
Cla_0571
ABC transporter, ATP-binding protein; Pfam matches to PF00005.18 ABC_tran, and to PF00005.18 ABC_tran.
       0.696
ftsH1
Cell division protein FtsH; Pfam match to PF00004.20 AAA; Belongs to the AAA ATPase family.
   
 0.659
ftsH2
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.659
Cla_0565
Conserved hypothetical protein.
       0.624
cmoB
Methyltransferase, putative; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
       0.624
grpE
Co-chaperone protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of AT [...]
  
  
 0.581
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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