| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiA | mnmC | Cla_0620 | Cla_0621 | Pfam match to PF01520.9 Amidase_3. | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.815 |
| amiA | npd | Cla_0620 | Cla_0619 | Pfam match to PF01520.9 Amidase_3. | Oxidoreductase (2-nitropropane dioxygenase family); Pfam match to PF03060.6 NPD. | 0.804 |
| amiA | pyrH | Cla_0620 | Cla_0615 | Pfam match to PF01520.9 Amidase_3. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.779 |
| amiA | rpoZ | Cla_0620 | Cla_0616 | Pfam match to PF01520.9 Amidase_3. | DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.788 |
| amiA | spoT | Cla_0620 | Cla_0617 | Pfam match to PF01520.9 Amidase_3. | ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.785 |
| amiA | tyrS | Cla_0620 | Cla_0618 | Pfam match to PF01520.9 Amidase_3. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.804 |
| mnmC | amiA | Cla_0621 | Cla_0620 | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Pfam match to PF01520.9 Amidase_3. | 0.815 |
| mnmC | npd | Cla_0621 | Cla_0619 | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Oxidoreductase (2-nitropropane dioxygenase family); Pfam match to PF03060.6 NPD. | 0.815 |
| mnmC | pyrH | Cla_0621 | Cla_0615 | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.788 |
| mnmC | rpoZ | Cla_0621 | Cla_0616 | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.793 |
| mnmC | spoT | Cla_0621 | Cla_0617 | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.793 |
| mnmC | tyrS | Cla_0621 | Cla_0618 | Conserved hypothetical protein (DUF752 domain protein); Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.815 |
| napA | napB | Cla_1018 | Cla_1015 | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | Periplasmic nitrate reductase, small subunit, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | 0.999 |
| napA | npd | Cla_1018 | Cla_0619 | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | Oxidoreductase (2-nitropropane dioxygenase family); Pfam match to PF03060.6 NPD. | 0.900 |
| napA | nrfA | Cla_1018 | Cla_1024 | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | Cytochrome c nitrite reductase, catalytic subunit NrfA; Pfam match to PF02335.6 Cytochrom_C552; Belongs to the cytochrome c-552 family. | 0.926 |
| napA | nrfH | Cla_1018 | Cla_1023 | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | Cytochrome c nitrite reductase, small subunit NrfH. | 0.963 |
| napB | napA | Cla_1015 | Cla_1018 | Periplasmic nitrate reductase, small subunit, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | 0.999 |
| napB | npd | Cla_1015 | Cla_0619 | Periplasmic nitrate reductase, small subunit, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | Oxidoreductase (2-nitropropane dioxygenase family); Pfam match to PF03060.6 NPD. | 0.900 |
| napB | nrfA | Cla_1015 | Cla_1024 | Periplasmic nitrate reductase, small subunit, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | Cytochrome c nitrite reductase, catalytic subunit NrfA; Pfam match to PF02335.6 Cytochrom_C552; Belongs to the cytochrome c-552 family. | 0.919 |
| napB | nrfH | Cla_1015 | Cla_1023 | Periplasmic nitrate reductase, small subunit, cytochrome c-type protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | Cytochrome c nitrite reductase, small subunit NrfH. | 0.976 |