STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msbAABC transporter, ATP-binding protein/permease MsbA, putative; Pfam matches to PF00664.14 ABC_membrane, and to PF00005.18 ABC_tran. (587 aa)    
Predicted Functional Partners:
cysS
cysteinyl-tRNA synthetase; Pfam matches to PF01406.10 tRNA-synt_1e, and to PF09190.2 DALR_2; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.860
mviN
Virulence factor protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
  
  
 0.833
pqqL
Peptidase, M16 family; Pfam matches to PF00675.11 Peptidase_M16, and to PF05193.12 Peptidase_M16_C.
   
   0.740
Cla_0625
Oxidoreductase, short chain dehydrogenase/reductase family; Pfam match to PF00106.16 adh_short.
   
 0.739
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 0.709
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
     
 0.706
ruvA
Holliday junction DNA helicase, DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.624
Cla_0635
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.621
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Pfam match to PF08245.3 Mur_ligase_M.
       0.621
Cla_0623
Peptidase M50, putative membrane-associated zinc metallopeptidase; Pfam match to PF02163.13 Peptidase_M50.
     
 0.615
Your Current Organism:
Campylobacter lari
NCBI taxonomy Id: 306263
Other names: C. lari RM2100, Campylobacter lari RM2100, Campylobacter lari str. RM2100, Campylobacter lari strain RM2100
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